منابع مشابه
The Level of Mesenchymal-Epithelial Transition Autophosphorylation is Correlated with Esophageal Squamous Cell Carcinoma Migration
Background: The MET receptor is a critical member of cancer-associated RTKs and plays an important role in different biological activities, including differentiation, migration, and cell proliferation. Methods: In this study, novel MET inhibitors were introduced and applied on esophageal squamous carcinoma cell line KYSE-30, and the level of proliferation and migration, as well as the activated...
متن کاملEpithelial and mesenchymal collective migration
143 The Rockefeller University Press $30.00 J. Cell Biol. Vol. 212 No. 2 143–155 www.jcb.org/cgi/doi/10.1083/jcb.201508047 Introduction The ability of cells to migrate is essential for physiological functions such as immunosurveillance, wound healing, and tissue morphogenesis during development. Pathological processes such as cancer invasion and metastasis also rely on the ability of malignant ...
متن کاملCollective migration of epithelial monolayers
Recent wound healing assays using monoloayers of epithelial cells have observed highly correlated, complex cell motions that persist well beyond the wound border. Here, I use the gross dynamical behavior of a single crawling cell with a simple model for cell-cell interactions to explain the migratory dynamics and long-range correlations that occurs in epithelial monolayers. Three reasonable phy...
متن کاملAirway Epithelial Cell Migration Dynamics
Cell spreading and migration associated with the expression of the 92-kD gelatinase (matrix metalloproteinase 9 or MMP-9) are important mechanisms involved in the repair of the respiratory epithelium. We investigated the location of MMP-9 and its potential role in migrating human bronchial epithelial cells (HBEC). In vivo and in vitro, MMP-9 accumulated in migrating HBEC located at the leading ...
متن کاملEpithelial to mesenchymal transitions and cell migration
Epithelial to mesenchymal transitions are prominent features of mammalian gastrulation and neural crest development, and are essential for the proper development of many organs and tissues. Moreover, most cancers derive from epithelial cells, and metastasis involves departure of these cells from their epithelium of origin and invasion of the surrounding tissue. It is known that epithelial to me...
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ژورنال
عنوان ژورنال: Ear, Nose & Throat Journal
سال: 2004
ISSN: 0145-5613,1942-7522
DOI: 10.1177/014556130408300802